Are nowadays laboratory indices useful in ovarian torsion?
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LAZĂR, Cornelia. Are nowadays laboratory indices useful in ovarian torsion? In: Міжнародний медико-фармацевтичний конгрес студентів і молодих учених: BIMCO, Ed. 6, 17 mai 2019, Chernivtsi. Chernivtsi: Bukovinian State Medical University, 2019, p. 3. ISSN 2616-5392.
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Міжнародний медико-фармацевтичний конгрес студентів і молодих учених 2019
Conferința " Міжнародний медико-фармацевтичний конгрес студентів і молодих учених"
6, Chernivtsi, Ucraina, 17 mai 2019

Are nowadays laboratory indices useful in ovarian torsion?


Pag. 3-3

Lazăr Cornelia
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 11 aprilie 2024


Rezumat

Ovarian torsion is a gynecological emergency encountered at any age when the blood flow to ovary is affected due to the rotation of the ovarian pedicle around its axis followed by ischemia. The state requires a quick diagnosis to avoid the loss of the organ and complications such as peritonitis, pelvic thrombophlebitis and death. The laboratory markers in clinical context faster the medical decision. Identification in the scientific literature of such markers could help the gynecologist. The purpose of the research was to find in the scientific international literature the serum markers for ovarian torsion that could ensure the correct diagnosis in the optimal time for the decision. The PubMed database was used to identify specific indices for ovarian torsion using the “adnexal torsion” and “ovarian torsion” keywords. The articles on ovarian torsion from the last twenty years were analyzed and were identified the blood markers. The ovarian torsion diagnosis can be a challenge for doctors as this clinical condition has nonspecific findings and this can delay the management. Till today the “gold standard” is laparoscopy, but to avoid unnecessary surgery, the scientists studied different laboratory indices that could be useful. Were identified the following markers: interleukin 6, ischemia modified albumin, D-dimers whose high level was found in adnexal torsion. A neutrophil-lymphocyte ratio > 3 was specific for women with torsion. Some patients could have mild leukocytosis, anemia, increased reactive protein C and pyuria without bacteriuria, but this are not specific for ovarian torsion and the physician must be cautious in such situations. As the management involves the detorsion of the ovary, the tumor markers such as CA125, AFP (alpha-fetoprotein) and HCG (human chorionic gonadotropin) can help to decide the correct surgery with the removal of the malignant structures if they are suspected. The doctors can decide to perform surgery in the presence of high levels of interleukin 6, ischemia modified albumin or Ddimers guided by the clinical context. As no high specific and sensitive marker for ovarian torsion was identified and assome laboratory findings can mislead doctors, the laparoscopy remain the sure tool in the diagnosis.