In Moldova, as well as in Europe, there are many invasive species that have acclimated here and rapidly spread aggressively occupying even larger areas, and their activity often influences negatively the ecosystems in which they grow. In the paper there are presented the results of the researches regarding the spreading, morphology, biology, ecology of the species Hyphantria cunea Drury (Omida păroasă a dudului), an important pest for the plantations in Moldova. The observations were made in period 2004 - 2008, in the orchards belonging to Moldova. The article contains experimental data of biological pest H. cunea development, biological plant protection and, control measures of pests are recommended. This work contains testing of biological preparation Virin ABB-3 -for elimination of H. cunea in laboratory and field conditions. The preparation is based on viruses of nuclear polyhedrosesis and granuoses with cumulative and synergetic action. Presently the investigation are being carried out the elaboration of other virus insecticide for control in the systems of integrated plant protection of different agricultural, ornamental and forest crops.