Clusters are geographic concentrations of interconnected companies, specialised suppliers, service providers, companies operating in related industries and associated institutions in certain fields, which compete with each other but also cooperate. They have proven successful economic advantages, becoming one of the most popular local and regional development concepts for both research and practice. Tourism activity capitalises on cluster initiatives, generalising complex, coherent and attractive products. The objective of this study is to highlight the key challenges of tourism clustering at international, regional and national levels.