Introduction. The contemporary development of nursing has initiated in today's practical medicine new possibilities of activity. This profession offers prospects to achieve a wide range of medical actions. In the national space so far, there have been no possibilities for training and application in clinical dentistry of the competences of the general nurse. At the same time, there is an acute need for nurses in this area. Aim of study. Relevation of the essential aspects of the activity of the general nurse within the local dental service. Method and materials. A literary review was made from pubmed databases, NCBI, MeSH, etc. The methods were applied: sociological and biostatistics. A questionnaire with 27 topics was compiled. 120 respondents participated in the survey. Results. In the research, mainly, the real possibilities of activity of the general nurses in the clinical dental units were analyzed. Along with the theoretical sources, we proceeded to the questionnaire of some categories of specialists, students and patients: dentists – 30; nurses – 30; generalist students and dentists – 30; former patients (25-60 years) – 30. At the same time, the directions of the involvement of nursing in clinical dentistry were structured. The survey showed, among other things, that nursing assistance offers greater treatment safety (85.9%) and a higher quality of patient care (80.8%). Thus, 91% respondents claim that the general nurse must demonstrate clinical thinking skills and maintaining calm in solving the emergency, etc. The promotion of optimal strategies regarding this quota of professionals by the health system will constitute a satisfactory contribution to the qualitative provision of medical services to the population. Conclusion. 1. Theoretical training within the specialty "General Nurse" and the practical skills obtained offer this category of specialists possibilities of activity in the most diverse fields of medicine, including dentistry. 2. The dental service in the Republic of Moldova offers the possibility of extensive application of competences: preparation of the patient to treatment; involvement with the doctor in medication; maintaining an adequate psychological support, etc. 3. General nurses are seen as health promoters with a special role in health education, fighting infections and preventing dental diseases. 4. The presence of the nurse inspires greater confidence in the replenishment of all clinical dental workmanship.