Diabetes mellitus is heterogenous pandemic metabolic disorder characterized by microvascular and macrovascular complications. Diabetic complications are derived from different pathophysiological processes. The most important are a chronically elevated blood glucose concentration due to insulin action, defective insulin secretion, or both. Additionally hyperglycaemia leads to damage of big blood vessels and heart or macrovascular complications, which are associated with cardiovascular diseases such as accelerated atherosclerosis, cardiomyopathy, myocardial infarction, and stroke. In this study we aimed to demonstrate an association between diabetes mellitus and cardiovascular diseases. We research the anamnesis, the clinical picture, the paraclinical methods, which demonstrate different changes that can confirmed these two pathologies.