Vulnerability is a characteristic of the human condition that includes various approaches. The bioethical knowledge applied in biomedical practice includes several stages. First, refers to monitoring medical research if it meets the moral normative consensus at the national and international level. Second, includes the analysis of the medical activity if it is respected the human values in the life and being of the patient. Next, tendency consist in improving the patient’s quality of life. Of course, all these stages arelinked between. However, the methods of achievement and evaluation are different, respectively the groups of trained subjects are different. An essential bioethical subject, in this context, is the issue of vulnerability in its overall interpretation, and the vulnerability of the liver patient in the pretransplant phase in particular. The training of bioethics in the analysis of the vulnerability of the liver patient is guided by the need to establish an integral image with possibilities of real applications in clinical activity.