Articolul precedent |
Articolul urmator |
377 9 |
Ultima descărcare din IBN: 2022-11-19 16:04 |
SM ISO690:2012 ICHIM, Mădălina, ISTRATENCO, Ala. Diagnosticul de laborator al sclerozei multiple. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 68. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Rezumat | ||||||
Background. The complexity of the clinical picture of multiple sclerosis can lead to delayed diagnosis. In this sense, the results of laboratory tests are useful in establishing the final diagnosis, choosing the right treatment and preventing long-term disability. Objective of the study. Evaluation of the recent literature on the laboratory diagnosis of multiple sclerosis. Material and Methods. In order to assess the need for laboratory tests in establishing the diagnosis of multiple sclerosis, a series of clinical protocols, scientific articles and recent experimental studies, both national and international, were evaluated and submitted to the study. Results. The most important laboratory tests in the diagnosis of multiple sclerosis are the biochemical testing of cerebral spinal fluid and the tests for quantitative and qualitative detection of intrathecal immunoglobulin G. Recent studies have shown an increase in the concentration of IgG in the cerebral spinal fluid in over 90% of patients. An innovative approach is to perform blood tests related to the presence of axonal damage protein (NF-L) in plasma. At the same time, new research in the field has proposed tests for the quantitative identification of myelin degradation products in the excreted urine of patients but which have not yet been subjected to clinical practice. Conclusion. There are currently no specific laboratory tests that would confirm the diagnosis of multiple sclerosis. Therefore, before establishing the diagnosis of multiple sclerosis it is necessary to exclude the possibility of other diseases. |
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Cuvinte-cheie multiple sclerosis, autoimmune disease, laboratory diagnosis, scleroza multiplă, afecțiune autoimună, diagnostic de laborator |
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