Are present the results of research and analysis of the antigenic spectrum of blood groups of animals in the Holstein
breed SRL 'DOCSANCOM' and STE 'Maximovca'. In both certified herds in EAB locus there is a high frequency of
antigen G2, O2, Y2, E'2, O ', Q', G ', which is characteristic for the Holstein breed, many breeds black-and-white root as
well as Moldavian type black-and-white cattle. By EAC-locus10 of the studied antigens R1 antigen is not revealed
among animals STE 'Maximovca'. High frequency of antigen E, R2, W and X2 characterizes the analyzed populations of
animals. For single-factor locuses EAJ, EAL, EAM and EAZ observed almost the same concentration of the
corresponding antigen in compared animal populations. The average frequency of antigen, or saturation of the studied
populations of antigenic factors in the population of animals herd SRL 'DOCSANCOM' is 23.7%, in the animal herds
STE 'Maximovca'-24, 5%. The genetic distance between populations of both analyzed populations is of little importance
- 0.0687, so they sufficiently close to each other. Concentration of main allele in the herd SRL 'DOCSANKOM' is
0,6213, the herd STE 'Maximovca'-0.6667, of rare 0.2129 and 0.2727 respectively. The degree of homozygosity in the
analyzed population is low, at 5.0% (SRL 'DOCSANKOM') and 6.0% (STE 'Maximovca').