Coronaviruses comprise a large family of RNA viruses that infect the digestive and respiratory epithelia and the nervous tissue.  The virus passes rarely from one species to another. Swine can develop four types of infections that are gendered by the transmissible gastroenteritis virus of swine (TGE), porcine epidemic diarrhea virus (PED), porcine respiratory coronavirus (PRC), and porcine hemagglutinating encephalomyelitis virus.  The genomic structure is very similar between the four coronaviruses, although their antigenic structure presents particularities for each species.   The aim of this study is to establish the proportion of digestive infections at piglets, by age, the mortality at piglets by pathologic disorder following the anatomoclinical and histo- pathological lesions from the small intestine, the mesenteric lymph nodes in piglets with gastrointestinal disorder. The epidemiological research was based on data registered in two intensive piggeries from the county of Iasi and Bacau. The highest incidence of mortality was noticed at piglets from 10 days to 3 weeks old and the main mortality cause was represented by gastrointestinal disorders.   The most frequent clinical signs were diarrhea, dehydration and intense weakness. The anatomoclinical examination revealed typical lesions mentioned in the description of TGE and PED – distended stomach that contains undigested milk, gas and fluid distended intestines, mesenteric lymphadenitis and pronounced atrophy of intestinal villi. Histo- pathological lesions were found in small intestine in jejunum: the intestinal villi were shortened; vacuolization was noticed at the enterocytes, hyaline inclusions, blunting of villi, atrophy of the muscular layer, distension of lymphatic vessels, mesenteric lymphadenitis. Clinical and pathological findings correspond to the characteristics of swine coronavirosis.