Molybdenum is a very important oligo-element which is involved in more than 50 enzymes. Therefore biological properties can be expected in many different domains as a function of the nature of the ligands coordinated to the Mo atoms. During this presentation, I will endeavor to illustrate the richness of the coordination chemistry we can develop with the small molecular clusters [MoV2O2S2]2+ and [MoV2O4]2+ and the resulting biological properties we can get with these compounds.[1-3] A first part of this presentation will be focused on synthesis, characterizations (NMR, MALTI-TOF) and properties of coordination complexes obtained by combining thiosemicarbazone ligands with [MoV2O2S2]2+. A second part will be devoted to more classical coordination compounds obtained with [MoV2O4]2+ which revealed very interesting and surprising properties for beekeeping.