| Conţinutul numărului revistei |
| Articolul precedent |
| Articolul urmator |
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 1732 19 |
| Ultima descărcare din IBN: 2021-11-22 02:31 |
| Căutarea după subiecte similare conform CZU |
| 616.24-002.5-036.22-07-085(478-21) (1) |
| Pathology of the respiratory system. Complaints of the respiratory organs (761) |
 SM ISO690:2012MALIK, Alina, USTIAN, Aurelia, LESNIK, Evelina, NIGULYANU, Adriana. The predictive factors for positive molecular-genetic assay in patients with pulmonary tuberculosis from Chisinau city. In: Curierul Medical, 2016, nr. 2(59), pp. 20-26. ISSN 1875-0666. |
| EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
| Curierul Medical | ||||||
| Numărul 2(59) / 2016 / ISSN 1875-0666 | ||||||
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| CZU: 616.24-002.5-036.22-07-085(478-21) | ||||||
| Pag. 20-26 | ||||||
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Background: One of the most important tuberculosis control action is the early detection, especially of multidrug-resistant tuberculosis. Cultural methods remain the golden standard for pulmonary tuberculosis diagnosis. The microscopic identification of acid-fast-bacilli in sputum is still a worldwide used method for TB detection. The low sensibility of conventional microscopic methods endangers the actual epidemiological situation. Starting with 2012, the genetic-molecular technology – Xpert MTB/RIF Assay - was implemented in the Republic of Moldova. The assessment of initial experience of Xpert MTB_RIF Assay is compulsory for improving the early case detection. The aim of the study is the assessment of extrinsic factors predictable in positive Xpert MTB_RIF patients. Material and methods: A retrospective, selective, descriptive and case-control study was performed. There were enrolled 361 new pulmonary tuberculosis patients, diagnosed and hospitalized in the Muncipal Clinical Hospital of Phthysiopneumology of Chisinau in the period of 01.01.2014 - 01.01.2015. The patients were disributed into 2 groups: I - 174 patients with positive Xpert MTB/RIF Assay result; II - 187 patients with negative Xpert MTB_RIF Assay result. Investigations were performed according to the National Clinical Protocol – 123 Tuberculosis in adults. results: The male gender was predominating above the female gender in both groups: 67,8% vs 32,2% in the 1st group and 55,6% vs 44,4% in the 2nd group. According to the economical status, disadvantaged patients were predominating in the 1st group (71,3%), as compared with the 2nd group (50.8%), with the degree of concludence, p<0,001. The hystory of household TB contact was predominating in the 1st group – 17,2% vs 9,1% in the 2nd group, (p<0.05). conclusions: The implementation of Xpert MTB_RIF Assay improves the early TB detection and the prompt initiation of an adequate treatment regimen, according to the susceptibility testing results. |
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| Cuvinte-cheie tuberculosis, risk factors, Xpert MBT/RIF Assay |
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Dublin Core Export
<?xml version='1.0' encoding='utf-8'?> <oai_dc:dc xmlns:dc='http://purl.org/dc/elements/1.1/' xmlns:oai_dc='http://www.openarchives.org/OAI/2.0/oai_dc/' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xsi:schemaLocation='http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd'> <dc:creator>Malic, A.M.</dc:creator> <dc:creator>Ustian, A.I.</dc:creator> <dc:creator>Lesnic, E.V.</dc:creator> <dc:creator>Niguleanu, A.</dc:creator> <dc:date>2016-04-28</dc:date> <dc:description xml:lang='en'>Background: One of the most important tuberculosis control action is the early detection, especially of multidrug-resistant tuberculosis. Cultural methods remain the golden standard for pulmonary tuberculosis diagnosis. The microscopic identification of acid-fast-bacilli in sputum is still a worldwide used method for TB detection. The low sensibility of conventional microscopic methods endangers the actual epidemiological situation. Starting with 2012, the genetic-molecular technology – Xpert MTB/RIF Assay - was implemented in the Republic of Moldova. The assessment of initial experience of Xpert MTB_RIF Assay is compulsory for improving the early case detection. The aim of the study is the assessment of extrinsic factors predictable in positive Xpert MTB_RIF patients. Material and methods: A retrospective, selective, descriptive and case-control study was performed. There were enrolled 361 new pulmonary tuberculosis patients, diagnosed and hospitalized in the Muncipal Clinical Hospital of Phthysiopneumology of Chisinau in the period of 01.01.2014 - 01.01.2015. The patients were disributed into 2 groups: I - 174 patients with positive Xpert MTB/RIF Assay result; II - 187 patients with negative Xpert MTB_RIF Assay result. Investigations were performed according to the National Clinical Protocol – 123 Tuberculosis in adults. results: The male gender was predominating above the female gender in both groups: 67,8% vs 32,2% in the 1st group and 55,6% vs 44,4% in the 2nd group. According to the economical status, disadvantaged patients were predominating in the 1st group (71,3%), as compared with the 2nd group (50.8%), with the degree of concludence, p<0,001. The hystory of household TB contact was predominating in the 1st group – 17,2% vs 9,1% in the 2nd group, (p<0.05). conclusions: The implementation of Xpert MTB_RIF Assay improves the early TB detection and the prompt initiation of an adequate treatment regimen, according to the susceptibility testing results. </dc:description> <dc:source>Curierul Medical 59 (2) 20-26</dc:source> <dc:subject>tuberculosis</dc:subject> <dc:subject>Xpert MBT/RIF Assay</dc:subject> <dc:subject>risk factors</dc:subject> <dc:title>The predictive factors for positive molecular-genetic assay in patients with pulmonary tuberculosis from Chisinau city</dc:title> <dc:type>info:eu-repo/semantics/article</dc:type> </oai_dc:dc>
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