Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
![]() |
![]() ![]() |
Ultima descărcare din IBN: 2021-11-22 02:31 |
Căutarea după subiecte similare conform CZU |
616.24-002.5-036.22-07-085(478-21) (1) |
Pathology of the respiratory system. Complaints of the respiratory organs (774) |
![]() MALIK, Alina, USTIAN, Aurelia, LESNIK, Evelina, NIGULYANU, Adriana. The predictive factors for positive molecular-genetic assay in patients with pulmonary tuberculosis from Chisinau city. In: Curierul Medical, 2016, nr. 2(59), pp. 20-26. ISSN 1875-0666. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Curierul Medical | ||||||
Numărul 2(59) / 2016 / ISSN 1875-0666 | ||||||
|
||||||
CZU: 616.24-002.5-036.22-07-085(478-21) | ||||||
Pag. 20-26 | ||||||
|
||||||
![]() |
||||||
Rezumat | ||||||
Background: One of the most important tuberculosis control action is the early detection, especially of multidrug-resistant tuberculosis. Cultural methods remain the golden standard for pulmonary tuberculosis diagnosis. The microscopic identification of acid-fast-bacilli in sputum is still a worldwide used method for TB detection. The low sensibility of conventional microscopic methods endangers the actual epidemiological situation. Starting with 2012, the genetic-molecular technology – Xpert MTB/RIF Assay - was implemented in the Republic of Moldova. The assessment of initial experience of Xpert MTB_RIF Assay is compulsory for improving the early case detection. The aim of the study is the assessment of extrinsic factors predictable in positive Xpert MTB_RIF patients. Material and methods: A retrospective, selective, descriptive and case-control study was performed. There were enrolled 361 new pulmonary tuberculosis patients, diagnosed and hospitalized in the Muncipal Clinical Hospital of Phthysiopneumology of Chisinau in the period of 01.01.2014 - 01.01.2015. The patients were disributed into 2 groups: I - 174 patients with positive Xpert MTB/RIF Assay result; II - 187 patients with negative Xpert MTB_RIF Assay result. Investigations were performed according to the National Clinical Protocol – 123 Tuberculosis in adults. results: The male gender was predominating above the female gender in both groups: 67,8% vs 32,2% in the 1st group and 55,6% vs 44,4% in the 2nd group. According to the economical status, disadvantaged patients were predominating in the 1st group (71,3%), as compared with the 2nd group (50.8%), with the degree of concludence, p<0,001. The hystory of household TB contact was predominating in the 1st group – 17,2% vs 9,1% in the 2nd group, (p<0.05). conclusions: The implementation of Xpert MTB_RIF Assay improves the early TB detection and the prompt initiation of an adequate treatment regimen, according to the susceptibility testing results. |
||||||
Cuvinte-cheie tuberculosis, risk factors, Xpert MBT/RIF Assay |
||||||
|
Crossref XML Export
<?xml version='1.0' encoding='utf-8'?> <doi_batch version='4.3.7' xmlns='http://www.crossref.org/schema/4.3.7' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xsi:schemaLocation='http://www.crossref.org/schema/4.3.7 http://www.crossref.org/schema/deposit/crossref4.3.7.xsd'> <head> <doi_batch_id>ibn-44559</doi_batch_id> <timestamp>1718265241</timestamp> <depositor> <depositor_name>Information Society Development Instiute, Republic of Moldova</depositor_name> <email_address>[email protected]</email_address> </depositor> <registrant>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“</registrant> </head> <body> <journal> <journal_metadata> <full_title>Curierul Medical</full_title> <issn media_type='print'>18750666</issn> </journal_metadata> <journal_issue> <publication_date media_type='print'> <year>2016</year> </publication_date> <issue>2(59)</issue> </journal_issue> <journal_article publication_type='full_text'><titles> <title>The predictive factors for positive molecular-genetic assay in patients with pulmonary tuberculosis from Chisinau city</title> </titles> <contributors> <person_name sequence='first' contributor_role='author'> <given_name>Alina</given_name> <surname>Malic</surname> </person_name> <person_name sequence='additional' contributor_role='author'> <given_name>Aurelia</given_name> <surname>Ustian</surname> </person_name> <person_name sequence='additional' contributor_role='author'> <given_name>Evelina</given_name> <surname>Lesnic</surname> </person_name> <person_name sequence='additional' contributor_role='author'> <given_name>Adriana</given_name> <surname>Niguleanu</surname> </person_name> </contributors> <publication_date media_type='print'> <year>2016</year> </publication_date> <pages> <first_page>20</first_page> <last_page>26</last_page> </pages> </journal_article> </journal> </body> </doi_batch>