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![]() SLIVINSKAYA-KURCHAK, K., KORZHINSKIY, Yu., LITVIN, G.. The level of zinc, vitamins A and E in the blood of neonates, who need a mechanical ventilation of lungs. In: Curierul Medical, 2013, nr. 4(56), pp. 7-10. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 4(56) / 2013 / ISSN 1875-0666 | ||||||
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Pag. 7-10 | ||||||
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Rezumat | ||||||
The number of infants who need mechanical lung ventilation in the neonatal period increases due to the increasing number of premature births. The prolonged lung ventilation is associated with the development of ventilation-associated complications. It is important to search the means of reducing the duration of traditional invasive ventilation and more common non-invasive methods of ventilation. The aim of this study is to determine the levels of vitamins A, E and zinc in the blood of neonates with respiratory disorders, needing lung ventilation, and evaluate the prognostic value of the above. According to the applied methods of respiratory therapy the infants have been divided into 2 groups: 1st – 17 children, who have had synchronized intermittent ventilation with pressure support (invasive ventilation), 2nd – 11 children with spontaneous breathing along with continuous positive airway pressure via nasal cannulas (non-invasive ventilation). The levels of vitamins A and E in serum have been determined by means of liquid chromatography, the levels of zinc − by means of atomic adsorption spectrophotometry. The results show that the serum level of vitamin A has been by 3.2 times, of vitamin E – by 2.1 times and of zinc – by 2.2 times lower in the neonates of group 1 than in group 2. Low serum levels of vitamins A, E and low zinc blood levels are associated with the necessity of more prolonged ventilation in neonates with respiratory disorders. We have concluded that using zinc, vitamins A and E in the complex treatment of neonates with respiratory disorders being on mechanical ventilation will help to reduce the duration of invasive ventilation and decrease the frequency of its complications. |
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Cuvinte-cheie Zinc, vitamins, neonates, mechanical lung ventilation |
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