Gonarthrosis represents one of the most frequent knee conditions, most commonly found in the 5th-6th life decades and not only, mainly in women, being the main cause of motoric disability in Europe, with a high impact on the social and economic status. The aim of the presentation is to aid the interdisciplinary team in interconnecting the imaging and clinical diagnosis of the osteo-articular system pathology. Content: The presentation reviews the radioimaging aspects of knee degenerative pathology. The imaging findings of a 35-year-old patient, known with right femur-coxal congenital subluxation, secondary left gonarthrosis and motoric disability are also presented as an illustration. The imaging technique included the pangonogram (hip-knee-ankle), which is an x-ray of the entire lower limb in orthostatism. The pangonogram allowed us to measure the hip-knee-ankle (HKA) angle, the internal mechanic alpha-femur angle, the Calton index – kneecap height, the beta – internal mechanic tibial angle and the gamma angle – tibial chute. Based on the imaging technique, there were highlighted changes in the bone structure of the left femural head, with a suspicious aspect of an aseptic necrosis, an internally curved tibia and peroneum on the left and secondary left gonarthrosis. The patient was admitted to the Orthopedics Department and underwent the necessary measurements for receiving a personalized knee prosthesis. Conclusions: This presentation highlights the challenging presentations of gonarthrosis and the modern techniques of diagnosis and treatment.