In recent years, the development of microelectronics, Internet of Things ( IoT ) and communication technologies in medical applications provided a good components and solution basis for successful development of wearable devices . These devices are used in different application with goal of diagnosing of pathological states and monitoring of the health status of chronic patients. In this article will be described a prototype of a telemetry system for remote monitoring of patient vital sign parameters (SpO2, heart rate/pulse, ECG, non-invasive blood pressure, temperature).