The paper presents multiannual data on the production and quality of winter barley kernels of the Dostoinii variety in multifactorial experiments carried out during 2015-2018, in the conditions of the central area of the Republic of Moldova. It was established that on average, on experience, the winter barley variety Dostoinii achieved the highest productions after pea as a precursor - 3346 kg/ha, significantly exceeding the production obtained after the precursor vetch with oats by 905 kg/ ha (27.0% ) and after sunflower with 979 kg/ha (29.3%). In the case of sowing terms, the optimal one was highlighted, ensuring higher yields after pea (3507 kg) and sunflower (2566 kg/ha), and after the spring vetch with oats the admissible one (2702 kg/ha). The share of influence on kernels production is 56.50% precursors, 26.03% sowing terms and 1.70% sowing density. The accumulation of protein substances was not significantly influenced by the studied factors, ranging between 12.20% and 13.64%. The maximum protein yield was recorded after the pea as a precursor, being 371.1 kg/ha from the higher grain production.