Climate change is causing increasingly dangerous extreme events globally, with floods having the potential to cause irreversible damage or complete destruction of cultural heritage sites. In Europe, floods are impacting a significant number of cultural heritage sites and buildings each year, prompting the creation of a Directive by the European Council to manage flood risk. Romania has experienced devastating floods in the mid to late 2000s, causing billions of euros in material damage, particularly in the Moldova region, which is of historical importance due to the large number of Cucuteni sites, a Neolithic archaeological culture dating from 5500 B.C. to 2750 B.C. Several other heritage sites, including Precucuteni and HorodișteaErbiceni/Godinești, are also located in the nearby vicinity of the river floodplain and are considered highly vulnerable. This study utilizes hydrological flood risk maps to assess the risk to cultural and historical heritage sites in the Jijia River Valley, which extends 180 kilometers, with its main course flowing parallel to the Prut River for almost 45 kilometers along its floodplain. The floodplain is wide, ranging from 0.5 to almost 3 kilometers, and is located exclusively within Botoșani and Iași county, partially or completely including 125 communes.