This article conducts a study on the accounting treatment of real estate investments. The research aims to identify both the similarities and the differences between the provisions related to the accounting regulations according to the national accounting framework compared to the international one established by IFRS. The research is based on the fact that in the Republic of Moldova, entities keep accounts based on national accounting standards, and public interest entities keep accounts based on IFRS. Scientific research methods are used in the study, such as: analysis of the national and international normative framework governing the study, synthesis of information, comparison to identify distinctive features, deduction of challenges. The result of the study points out the similarities and differences related to the accounting of real estate investments according to the provisions of the National Accounting Standards versus IFRS.