In the paper are described the results of the study on the state and development of the natural protected areas in the Republic of Moldova. The paper presents the analysis present state of protected areas at global, European and national level, as well as some visions of their perspectives in the Republic of Moldova. In the final part of the paper are presented some conclusions and proposals on the general aspects for to achieve more performance in policy and practical activities for the enlargement of natural protected areas in the Republic of Moldova in accordance with European and international requirements.