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SM ISO690:2012 NACU, Gabriela. Recurrent stroke in young patients. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 236. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | |||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | |||||||
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Pag. 236-236 | |||||||
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Background. According to the studies, approximately 10% of ischemic strokes occur in people aged less than 50 years. The risk of recurrent stroke in young stroke survivors varies from 9.4% in the next 5 years, up to 19.4% in the next 20 years. Objective of the study. To analyze the symptomatology presented by young patients (<50 years) with recurrent stroke, and to compare them, with clinical signs presented by people of the same age category, with the first-ever stroke. Material and Methods. A retrospective analysis of 1687 medical records of patients with ischemic stroke was performed from January 2018 to December 2019. 56 patients (≤ 50 years old) were included in the study. Risk factors, clinical signs, neuroimaging were analyzed - all of these were stratified by the presence of recurrent stroke criteria. SPSS Statistics, Version 25.0 was used. Results. The cohort study consisted of 2 groups: the first group- patients with the first-ever stroke (46); the second one– patients with recurrent stroke (10). The frequency of clinical signs between these two groups was compared: speech disorders (30.0% vs. 37.0%); sensitivity disorders (20.0% vs. 13.0%); cranial nerve damage (20.0% vs. 15.2%); paresis/ plegia (90.0% vs. 65.2%); bulbar syndrome (20.0% vs. 28.3%). Changes on cerebral CT: leukoaraiosis (30.0% vs. 28.3%); old infarcts on imaging (80.0% vs. 6.5%, t = 5.29, ˂0.001); Doppler Ultrasound of intra and extracranial arteries: stenotic atherosclerosis (42.9% vs. 40.5%); vertebral artery hypoplasia (42.9% vs. 32.4%). Conclusion. Recurrent ischemic stroke in young patients has more variable symptoms, with a more unfavorable prognosis if compared with the first ever stroke in the same category of patients. So, it requires the establishment of recurrence risk factors and an efficient secondary prophylaxis |
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Cuvinte-cheie stroke, ischemia, young, recurrent., AVC, ischemie, Tineri, recurent |
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<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xmlns='http://datacite.org/schema/kernel-3' xsi:schemaLocation='http://datacite.org/schema/kernel-3 http://schema.datacite.org/meta/kernel-3/metadata.xsd'> <creators> <creator> <creatorName>Nacu, G.</creatorName> <affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation> </creator> </creators> <titles> <title xml:lang='en,ro'>Recurrent stroke in young patients</title> </titles> <publisher>Instrumentul Bibliometric National</publisher> <publicationYear>2021</publicationYear> <relatedIdentifier relatedIdentifierType='ISBN' relationType='IsPartOf'>978-9975-82-223-7 (PDF).</relatedIdentifier> <subjects> <subject>stroke</subject> <subject>ischemia</subject> <subject>young</subject> <subject>recurrent.</subject> <subject>AVC</subject> <subject>ischemie</subject> <subject>Tineri</subject> <subject>recurent</subject> </subjects> <dates> <date dateType='Issued'>2021</date> </dates> <resourceType resourceTypeGeneral='Text'>Conference Paper</resourceType> <descriptions> <description xml:lang='en' descriptionType='Abstract'><p>Background. According to the studies, approximately 10% of ischemic strokes occur in people aged less than 50 years. The risk of recurrent stroke in young stroke survivors varies from 9.4% in the next 5 years, up to 19.4% in the next 20 years. Objective of the study. To analyze the symptomatology presented by young patients (<50 years) with recurrent stroke, and to compare them, with clinical signs presented by people of the same age category, with the first-ever stroke. Material and Methods. A retrospective analysis of 1687 medical records of patients with ischemic stroke was performed from January 2018 to December 2019. 56 patients (≤ 50 years old) were included in the study. Risk factors, clinical signs, neuroimaging were analyzed - all of these were stratified by the presence of recurrent stroke criteria. SPSS Statistics, Version 25.0 was used. Results. The cohort study consisted of 2 groups: the first group- patients with the first-ever stroke (46); the second one– patients with recurrent stroke (10). The frequency of clinical signs between these two groups was compared: speech disorders (30.0% vs. 37.0%); sensitivity disorders (20.0% vs. 13.0%); cranial nerve damage (20.0% vs. 15.2%); paresis/ plegia (90.0% vs. 65.2%); bulbar syndrome (20.0% vs. 28.3%). Changes on cerebral CT: leukoaraiosis (30.0% vs. 28.3%); old infarcts on imaging (80.0% vs. 6.5%, t = 5.29, ˂0.001); Doppler Ultrasound of intra and extracranial arteries: stenotic atherosclerosis (42.9% vs. 40.5%); vertebral artery hypoplasia (42.9% vs. 32.4%). Conclusion. Recurrent ischemic stroke in young patients has more variable symptoms, with a more unfavorable prognosis if compared with the first ever stroke in the same category of patients. So, it requires the establishment of recurrence risk factors and an efficient secondary prophylaxis</p></description> <description xml:lang='ro' descriptionType='Abstract'><p>Introducere. Conform studiilor efectuate, aproximativ 10% dintre accidentele vasculare cerebrale ischemice apar la persoanele cu vârsta sub 50 de ani. Riscul de AVC recurent la pacienții tineri variază de la 9,4% în primii 5 ani, până la 19,4% în primii 20 de ani. Scopul lucrării. Analiza simptomatologiei prezentate de pacienții tineri (< 50 ani) cu AVC recurent, prin compararea clinicii date, cu clinica prezentată de persoanele de aceeași categorie de vârstă cu AVC primar. Material și Metode. A fost efectuată analiza retrospectivă a 1 687de fișe medicale ale pacienților cu AVC ischemic, din ianuarie 2018- până în decembrie 2019. 56 de pacienți (≤ 50 ani) au fost incluși în studiu. Au fost analizați factorii de risc, semnele clinice, neuroimagistica – toate fiind stratificate după criteriul prezenței AVC-ului repetat. A fost utilizată Statistica SPSS, Versiunea 25.0. Rezultate. Studiul a constat din 2 grupuri: primul – AVC primar depistat (46 de pacienți) și grupul II – AVC repetat (10 pacienți). A fost comparată frecvența semnelor clinice din cadrul AVC-ului repetat și primar: tulburări de vorbire (30.0% vs 37.0 %); tulburări de sensibilitate (20.0% vs 13.0 %); afectarea nervilor cranieni (20.0% vs 15.2 %); prezența parezei/plegiei (90.0% vs 65.2 %); sindrom bulbar (20.0% vs 28,3 %). TC cerebrală leucoaraioza (30.0% vs. 28,3 %); focare vechi (80.0% vs 6,5%, t=5.29, ˂0.001). Dopplerografia vaselor intra- și extracraniene: ateroscleroza stenozantă (42,9% vs 40,5%); hipoplazia arterei vertebrale (42,9% vs 32,4%). Concluzii. Accidentul vascular ischemic recurent la pacienții tineri prezintă o clinică mai vastă, cu prognostic mai nefavorabil comparativ cu cea din AVC-ul primar, ceea ce necesită stabilirea factorilor de risc de recurență și a unei ulterioare profilaxii secundare.</p></description> </descriptions> <formats> <format>application/pdf</format> </formats> </resource>