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SM ISO690:2012 SMELANSKY, Emily Ghenady, FEGHIU, Iuliana. Modificările tonusului cardiac vegetativ după intubația endotraheală în cursul inducției anesteziei generale cu Propofol și Fentanil. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 60. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Background. Induction of general anesthesia, especially the stage of endotracheal intubation is frequently associated with changes in heart rhythm and cardiac arrhythmias triggered by changes in vegetative tonus of the heart. Objective of the study. Detection of changes in vegetative tonus of the heart by spectral analysis of heart rate variability after endotracheal intubation during induction of general anesthesia with propofol, fentanyl and myorelaxation with atracurium. Material and Methods. The study was approved by the Ethic Committee SUMF “N. Testemițanu”. Changes in vegetative tonus of the heart were appreciated by changes in heart rate variability with ECG Holter. There were calculated LFun, HFun and the LFun/HFun ratio. Statistical analysis was performed with the program Prism, version 8,0. Results are presented as mean with 95% confidence interval. Results. The study group comprises 47 patients with age 37,5±11,9 years. BMI 24,6±3,4 kg/m2. Initial LFun/HFun ratio was 2,7±0,3, proving the presence of enhanced sympathetic heart tonus. Induction of general anesthesia was performed with propofol 2.5 mg/kg combined with fentanyl 0,2-0,3 mkg/kg, myorelaxation was done by administration of atracurium 0,5 mg/kg. After endotracheal intubation the value of LFun was 68,7 (95%CI 63,3-74,1), value of HFun was 31,3 (95%CI 25,9-36,7) and the value of ratio LFun/HFun was 4,1 (95%CI 2,8-5,4) such proving the augmentation of sympathetic heart tonus. In 8 patients (17,0%) there was attested sinus tachycardia. Conclusion. Endotracheal intubation after induction of general anesthesia with propofol, fentanyl and myorelaxation with atracurium is associated with enhancement of sympathetic tonus of the heart. |
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Cuvinte-cheie endotracheal intubation, vegetative heart tonus, intubație endotraheală, tonus cardiac vegetativ |
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