Articolul precedent |
Articolul urmator |
523 9 |
Ultima descărcare din IBN: 2024-03-18 21:38 |
SM ISO690:2012 ROTARU, Corneliu, BIVOL, Maria, IACONI, Oana-Simina, BURDUNIUC (POPA), Olga. Formarea biofilmelor– unul din factorii de virulență ai fungilor. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 177. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||||
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Pag. 177-177 | |||||||
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Background. The biofilms’ formation plays a significant role in the pathogenicity of fungi and the development of human infections. Preventive measures are becoming less effective due to the increased resistance of biofilms to both antifungal drugs and disinfectants. Objective of the study. Carrying out an analysis of the literature on medically important fungal virulence factors, including the formation of biofilms. Material and Methods. The paper analyzes the most relevant and up-to-date publications in the medical literature in the country and abroad, using online medical databases: Medline (Pubmed), Springer Link, ScienceDirect and Web of Science. Results. The analyzed studies disclose evidence that proves the importance of favorable factors (organ transplantation, antitumor therapy etc.) in the spread of fungal infections. The ability of fungi to form biofilms and the presence of other virulence factors (thermotolerance, ability to produce melanin, mannitol and catalase, the ability to obtain Fe, the ability to change their shape) stimulates the survival and persistence of fungi in the host organism. The property of fungi, especially for Candida genus, to form biofilms is clinically significant and can cause persistent candidiasis as a result of increased resistance to antifungal agents. Conclusion. Fungal infections are part of emerging infections group and have an increasing ratio among communicable diseases. The ability of fungal species to form biofilms is an important pathogenicity factor, which must be the main target of antifungal treatment. |
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Cuvinte-cheie fungal biofilms, fungi, biofilms, biofilme fungice, Fungi, biofilme |
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