Starting from the increasing impact of harmful organisms on the background of climate change, there is an increasing need to strengthen food security and food safety, which is made possible by expanding the range of environmentally friendly means. The application of control methods, including the destruction of harmful organisms, causes various problems, including ethical ones, related to the human right to reduce or control the development of some entities by others. The article contains a systemic approach to the relationships between harmful organisms and biological means of plant protection in the four types of biological control: natural, conservation, augmentation and import, in which ethical concerns have steadily increased. Strengthening plant protection for plant health and the systemic approach creates premises for sustainable development based on organic farming.