After disintegration of the Soviet Union Moldova is facing number of social, economic and also territorial problems. Nowadays, together with Albania, Moldova is the poorest country in Europe, GDP per 1 citizen in 2008 was only 1.470 USD, 3.210 USD in the purchasing power parity respectively. More than 30 % of population lives in the poverty and according to HDI index assessment Moldova is on 131st place and which is the level of countries from poor African region. Agriculture and food are dominant in Moldovan national economy with the share of 33 % of GDP and 65 % of the export. One of the major weaknesses of agricultural sector of Moldova is an insufficient access to information sources which are essential, that’s why it is important to implement new modern technologies and know-how transfer in rural areas of Moldova for reduction of lack of information sources, which could make all efforts within the agricultural environment of the country easier and more effective. The paper relates the Marketing Information System (MIS) development and establishment in Republic of Moldova, which will be easily accessible for users anywhere in Moldova, especially in rural areas and which would be simple, reliable and would provide bilateral or multilateral communication and also with potential for future development.