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Ultima descărcare din IBN: 2024-04-10 19:57 |
SM ISO690:2012 POPESCU, Victor, ŢÎBÎRNĂ, Andrei, BUTOVSCAIA, Cristina. Particularităţile unor profiluri metilice ale promotorului genei p15 la pacienţii cu cancer tiroidian
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2010, nr. 3(11), pp. 351-356. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 3(11) / 2010 / ISSN 1857-1719 | ||||||
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Pag. 351-356 | ||||||
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Rezumat | ||||||
Peculiarities of some methylic profiles of p15 gene promoter in patients with thyroid cancer
In this study we have obtained some methylic profiles in DNA extracted from normal
tissue and thyroid malignant tumors (various morphologic subtypes). We have identified
differences in the methylic profile of p15 gene promoter of the thyroid tumors compared with the profile of normal thyroid cells (peritumoral tissue). In conclusion we sustain that MM methylic profile of p15 gene promoter can be used as a high-risk molecular marker for the examined person who can be affected with thyroid cancer refering the day of sample collection. |
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