The main objective of this study is to analyze the food security resilience of the Republic of Moldova. For this reason, it is essential to establish the interconnections between food security and foreign trade of the Republic of Moldova in the actual circumstances on the external market. On the one hand, agricultural economic agents faced the loss of traditional export markets. The most vulnerable category in this regard is 08. Edible fruits and nuts; peels of citrus fruits or melons, which in 2021 constituted 7.40% of the total exports. About 52.15% of the export of this category was directed in 2021 in Russian Federation. On the other hand, the increase in the prices of agri-food products has intensified the risks of excessive growth of exports and their potential insufficiency for consumption on the domestic market. In conclusion, it is highlighted that the situation in the region of our country generates vulnerabilities with a substantial impact on food security.