Study of the acidopoietic function of the stomach in the normosthenic type of constitution
Закрыть
Articolul precedent
Articolul urmator
215 2
Ultima descărcare din IBN:
2024-01-25 11:18
Căutarea după subiecte
similare conform CZU
616-056.25 (14)
Патология. Клиническая медицина (7179)
SM ISO690:2012
BABILEVA, Anastasia. Study of the acidopoietic function of the stomach in the normosthenic type of constitution. In: Natural sciences in the dialogue of generations, 14-15 septembrie 2023, Chişinău. Chişinău: Centrul Editorial-Poligrafic al USM, 2023, p. 108. ISBN 978-9975-3430-9-1.
EXPORT metadate:
Google Scholar
Crossref
CERIF

DataCite
Dublin Core
Natural sciences in the dialogue of generations 2023
Conferința "Natural sciences in the dialogue of generations"
Chişinău, Moldova, 14-15 septembrie 2023

Study of the acidopoietic function of the stomach in the normosthenic type of constitution

CZU: 616-056.25

Pag. 108-108

Babileva Anastasia
 
Moldova State University
 
 
Disponibil în IBN: 18 octombrie 2023


Rezumat

The objective of the research is to identify the particularities of the acidopoietic stomach function in persons with a normometabolic status. The experiment was performed on laboratory animals (white Wistar rats). The acidopoietic activity is determined by means of probes with two olives and the acidogastrometer АGM-10-01. The atropine test made it possible to distinguish basal acidogenesis (continuous) humoral and reflective nature. In the first case, acidogenesis is mainly caused by histamine and the like. An acidogenesis like that is not blocked by atropine. But if acidogenesis is brought about by reflexive and conditioned reflexive influences, then acidogenesis is blocked by atropine. The research conducted provided the following findings: the acidity of the gastric juice in the region of the glands with gastric secretion in people with normometabolic status of the body during the observation period (50 min) varied within the limits of the рН value of 1.3±0.17 – 1.6±0.26. The positive atropine test resulted in a decrease in the acidity of the stomach content from a pH of 1.35±0.14 at baseline to a pH of 2.5±0.09 and 2.3±0.15 at 20 and 30 minutes of observation. This indicates the activity of the parasympathetic division of the region of the autonomic (vegetative) nervous system in the neurohumoral complex of acidogenesis in individuals with a normometabolic status of the body. Indications of pH-metry in the body of the stomach in rats without the atropine test (1.3±0.17-1.6±0.26 рН), obtained against the background of the normal functional state of the stomach, should be classified as sanogenic limits of acidogenesis for people with normometabolic status of the body. The prevalence of the reflector bond in the neurohumoral complex of mechanisms in people with normometabolic status allows us to label it as a neurohumoral type of secretion. The dynamics of the pH change in the pyloroantral area of the stomach in patients with normometabolic status indicate a high neutralization potential of the antrum. The excess of pH greater than 5.0 in the antrum and the difference in pH of 3.8–4.4 between the acidogenic and antral zones allow us to state that the neurohumoral type of secretion possesses compensated acidogenesis. Thus, the experimental data made it possible to identify of the functional features of stomach acidogenesis in persons with a normometabolic state of the body. The positive test with atropine in the differentiation of basal acidogenesis demonstrates the presence of the reflector bond in the neurohumoral mechanism of acidogenesis in the normometabolic status of the organism.

Cuvinte-cheie
acidopoietic function, stomach, normometabolic, constitution, atropine, pH