Migration, human mobility and population movements remain among the defining characteristics of human society. These phenomena are driven by an increasingly globalized international context and an appropriate technological development, with a lot of consequences for countries of origin and countries of destination. Republic of Moldova is considered to be a country with a high emigration rate. It has been facing several problems related to population emigration since the late 1990s. At the moment, there is a large presence of Moldovan citizens in several countries. This article refers to the process of integration of Moldovan migrants, their attempts to settle in the host country, to adapt to the new living and working conditions, new political, social, economic or cultural context, etc. The term integration is complex, with multiple meanings, there are also a variety of theories and approaches. In the context of research on the integration process of migrants, a special role belongs to the processes of assimilation and acculturation. The research study was carried out by applying a series of methods: systemic, statistical, historical, comparative, etc. Among the European countries, the largest communities of emigrants from the Republic of Moldova are currently in Italy. Analyzing the evolution of the communities of Moldovan citizens in Italy, were highlighted the characteristics of the stabilization and consolidation phase. In the case of the integration process, the risk factors must be taken into account.