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SM ISO690:2012 CIUTAC, Ion. Current Concept of Etiology and Pathogenesis in Acute Obstructive Cholecystitis. In: Curierul Medical, 2011, nr. 2(320), pp. 22-29. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 2(320) / 2011 / ISSN 1875-0666 | ||||||
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Pag. 22-29 | ||||||
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403 older patients with acute calculous cholecystitis (catarrhal and destructive) with severe comorbid diseases and increased risk of surgery
underwent minimally invasive laparoscopic cholecystolithostomy performed as a preliminary or definitive stage of surgical treatment. Based on
observational methods stemming from this laproscopic technique, the role of mechanical obstruction (calculous cholecystitis) in the onset of an
acute cholecystitis attack has been described in detail. Furthermore, two novel factors are identified: the inflammation of infundibular-cystic
junction mucosa (inflammatory factor) and the increased viscocity of the bile (colloidal factor). The role of these in acute cholecystitis and on
the development of intravesicular hypertension is described. All of the factors – mechanical, inflammatory, colloidal – form a vicious cycle in
acute cholecystitis, their interdependency having a direct action on the progression of disease. The major role of laparoscopic bile decompression
in solving the acute obstructive cholecystitis in high-risk patients has been emphasized. |
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Cuvinte-cheie acute obstructive cholecystitis, impacted calculus, free calculus, inflammation of infundibular-cystic junction mucosa, calculous cholecystitis |
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