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Ultima descărcare din IBN: 2024-03-21 10:48 |
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618.3-06:616.151.5 (2) |
Medical sciences (11143) |
Pathology of the circulatory system, blood vessels. Cardiovascular complaints (975) |
SM ISO690:2012 VISTERNICEAN, Elena, MOŞIN, Veaceslav, HOTINEANU, Alina, CREŢU, Adrian. Polimorfismele genetice MTHFR C677T, MTHFR A1298C, MTRR A66G şi MTR A2756G la femeile cu avort spontan recurrent. In: Buletin de Perinatologie, 2017, nr. 2(74), pp. 36-42. ISSN 1810-5289. |
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Buletin de Perinatologie | ||||||
Numărul 2(74) / 2017 / ISSN 1810-5289 | ||||||
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CZU: 618.3-06:616.151.5 | ||||||
Pag. 36-42 | ||||||
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The frequency of mutated MTHFR genotypes: 677TT was 14,0% (95%CI 4,39 – 23,61) and 1298CC was 10% (95%CI 1,69 – 18,31). Compound heterozygosity 677CT/1298AC was detected in 28,0% (95%CI 15,56 – 40,44). No patients had the 677TT/1298CC genotype. The frequency of MTR 2756GG genotype was 6,0% (95%CI -0,58 – 12,58) and the MTRR 66GG genotype was present in 20,0% (95%CI 8,92 – 31,08). Conclusions. Polymorphisms in genes MTHFR, MTR and MTRR were detected in 98,0% (95% IC 94,12 – 101,88). |
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Cuvinte-cheie recurrent miscarriage, MTR, MTRR, MTHFR, thrombophilia |
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