Gout and metabolic syndrome
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ROTARU, Larisa, GROPPA, Liliana, RUSSU, Eugen, CHIŞLARI, Lia, SÂRBU, Oxana, CORNEA, Cornelia. Gout and metabolic syndrome. In: By promoting excellence we prepare the future, Ed. 2, 28 februarie - 2 martie 2022, Iași. Iași : Apollonia University of Iasi, 2022, Ediţia 2, Vol. 26, p. 324.
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By promoting excellence we prepare the future
Ediţia 2, Vol. 26, 2022
Congresul "By promoting excellence we prepare the future"
2, Iași, Romania, 28 februarie - 2 martie 2022

Gout and metabolic syndrome


Pag. 324-324

Rotaru Larisa, Groppa Liliana, Russu Eugen, Chişlari Lia, Sârbu Oxana, Cornea Cornelia
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 17 iunie 2024


Rezumat

Objectives: To determine the prevalence of metabolic syndrome (MS) in patients with gout, and study its manifestations depending on the nature of renal disease. Materials and methods: 365 patients with gout have been examined: 310 with chronic gout, 55 with acute gout. Age from 18 to 81 years old. Disease duration was between 1 and 42 years. Results and discussion: Joint involvement: the first MTP joint – 298 (81,6%), by ankle joints in 186 (50,9%), knee joints in 159 (43,5%), the joints of the upper limbs – 119 (32,6%) patients. Kidney involvement – 174 (47,7%) patients had tubular‑interstitial nephritis with uric acid diathesis, 162 (44,4%) patients had nephrolithiasis. MS was diagnosed in 189 (51,8%) patients with gout, a Waist Circumference of > 94 cm was seen in 189 (51,8%), triglycerides> 1.7mmol/l in 178 (48,8%), glucose> 6.1 mmol/l in 161 (44,1%) patients. Decreased glomerular filtration rate below 60 ml/min – 164 (44,9%) of gout patients with MS, 48 (13,1%) patients without MS. Systolic BP> 135 mmHg – 274 (75%) patients. Conclusion: All of the above results correspond to data from international studies pointing to the fact that the presence of the metabolic syndrome in patients with gout leads to organ damage, regardless of geographic location, but depends on disease duration.

Cuvinte-cheie
gout, metabolic syndrome, case study