First described by Rokitansky in 1860, endometriosis remains an enigmatic disease. It is a common, chronic condition that affects approximately 10% of women of reproductive age. EMS can significantly impact a woman’s quality of life, her fertility and ability to work. EMS’s clinical presentations are various, but they are essential characterized by a pain syndrome and disorder of menstrual cycle. Four basic types of EMS lesions have been described. They are frequently associated in the same patient: Superficial implants: are the most frequent lesions encountered. The classical appearance of SI is bluish or blue-black or “powder-burn” lesions. Nonpigmented, also called atypical or subtle, lesions have been described. These latter lesions are early stages of the disease and have been proved to be very active. They are more frequently encountered in adolescents or young women. Endometriotic cysts: frequently with associated adhesions, contain a chocolate-like fluid. Deep infiltrating endometriosis: is defined as lesions infiltrating the peritoneum, or the serosa of vital organs, greater than 5 mm. Typically DIE is a nodular blend of fibromuscular tissue and adenomyosis, located in the uterosacral ligaments or the rectovaginal septum. DIE is apparently more associated with severe pain symptoms. Adhesions. All types of ED lesions have similar morphogenesis features, including the various form of proliferation,secretion, regression, wave-like courses of dishormonal morphogenetic manifestation within one organ. Typical for all EMS’slesions pathologic synthesis of aromatase cytochrome P-450 promotes the local estrogens synthesis from androgens, transitionof endometrioid heterotopias to the quite different level of existence and self-regulation contributing autonomouswave-like chronic EMS’ clinic course. So the separation of various ED’s morphofunctional forms, its clincophatological features and intensityits morfofunctional activity is necessary. It will help to determine future manifestations of the disease, to establishcorrelation between lesion types and symptoms such as pain, dyspareunia, infertility and dysmenorrhea. Also a better understandingof lesions, their appearance and evolution can help to develop a better plan of treatment which can prevent recurrencesand atypical growing.