Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
53 0 |
SM ISO690:2012 SAPOJNIC, Nadejda, CARAUŞ, Alexandru, MOSCALU, Vitalie, BÎTCA, Angela, SIMIONOV, Lilia, MOISEEVA, Anna, CHETRUŞ, Olga, RUSSU, Eugen, CARAUŞ, Mihaela, DURNEA, Aliona. Arterial stiffness and diastolic function alteration in essential hypertension. In: European Journal of Heart Failure, 2020, vol. 20, supl. nr. 1, p. 191. ISSN 1388-9842. |
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European Journal of Heart Failure | ||||||
Volumul 20, Supliment nr. 1 / 2020 / ISSN 1388-9842 /ISSNe 1879-0844 | ||||||
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Pag. 191-191 | ||||||
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Recent data have suggested that both increased arterial stifness and diastolic dysfunction (DD) serve as contributors to the development of heart failure. Several studies have shown that the extent of DD could be interdependent with the severity af arterial stiffness. AIM: to investigate whether there is a relationship between arterial stiffness and severityof LV diastolic dysfunction. METHODS: 101 HT patients (mean age 51.08±0.79 yrs; 48.51% of men, SBP/DBP: 202.49±7.41/106.7±5.54mmHg, BMI- 29.38±0.22 kg/m2) without any co-morbidities underwent ABPM, TE and arterial stiffness evaluation. C1 and C2 were derived from pulse wave analysis based on a modified Windkessel model and constitue for C1:10.7± 0.5 ml/mm Hg×10, and for C2: 4.5± 0.3 ml/mm Hg×100. Alterated arterial elasticity was considered for C1 < 10 ml/mm Hg×10, C2 <6 ml/mm Hg×1. DD patterns were appreciated according to ASE/EACVI 2016 guidline. Correlation analysis was performed using Pearson s test. Results: The extent of arterial stiffness and the degree of diastolic dysfunction demonstrated a statistically significant correlation (p < 0.001). A more advanced patterns of diastolic dysfunction demonstrated a particularly strong relationship with higher arterial stiffness (Fig. 1, Tab. 2,). Conclusion: In hypertensives, reduction in arterial elasticities properties is associated with LV diastolic dysfunction, and this association appears to have particularly strong relationship with extent of diastolic function’s alteration. The more advanced patterns of diastolic dysfunction occurred, the stronger is the interdependence with arterial stiffness indices. |
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