Introduction. Approximately 60% of the population of reproductive age has a high intake of supplements. Among the most popular sports supplements used are protein (51.2%), creatine (22.9%) and pre-workout/energy (20.7%), and the reasons for taking the supplements were to improve exercise recovery (52 .6%), general health (51.4%) and increased muscle mass/strength (41.7%). However, little is known about how consumption of these products affects male reproductive health. Material and methods. A detailed review of the specialized literature was carried out to detect all available documents that investigated adverse effects of dietary supplements and their mechanism on male fertility. A literature search was performed using the Google Scholar, PubMed, SCOPUS and Science Direct databases without time limitations using the keywords: «sport suppliments,» „caffeine,” «creatine,» «protein powders,» «sperm quality,» and «male fertility». Results. Research shows that caffeine can damage sperm cells by breaking up their DNA and causing them to have an abnormal number of chromosomes, caffeine intake above 200mg per does appear to affect reproductive hormones particularly associated with a decrease in oestradiol (oestrogen) concentration, at the same time no association was found between caffeine consumption and any fertility related outcomes. Creatine can increase the level of adenosine triphosphate (ATP) in sperm cells, thereby increasing motility. The right amounts of BCAAs in whey protein powders have a synergistic effect on sperm function and testosterone production, resulting in increased fertility. Protein supplements do not have a direct negative effect on male fertility, considering that 23 of 24 protein supplements contained undeclared anabolic androgenic steroids, it may affect reproductive system. Abstinence from protein supplements resulted in a significant increase in median sperm concentration, which was 2.6 times higher than the baseline median sperm concentration, another study found protein does not significantly impair sperm quality and may even improve sperm motility. Conclusions. Most supplements used in sports are rarely discussed when it comes to male fertility and there is not enough research on this topic. However, not all supplements are harmful to fertility, some of them appear to have a relatively neutral or have been shown to improve not only sperm concentration, but also motility and morphology.