Introduction. Cerebral palsy (CP) is one of the diseases that is often associated with epilepsy, which is quite common in children with developing CP. Often seizures can be caused by brain abnormalities found in children with CP. Many of the children diagnosed with PC are diagnosed late with epileptic syndromes. The purpose of this study was to describe the prevalence, syndromes and evolution of epilepsy in children with CP due to various causes. Material and methods. For this population-based cohort study, children with CP addressed to IMSP BMI from R were selected. Moldova (aa. 2019 – 2022). Medical records (and interviews from caregivers) of children with CP, electroencephalographic records (EEG) and MRI brain scans were reviewed. 86 (b – 47, f – 39) children with cerebral malformative syndromes and structural changes in the brain associated with perinatal damage (35-born prematurely). Statistical method: t-student test. Results: out of all the reviewed files, 38 (44%) cases showed manifestations of hypoxic-ischemic perinatal suffering of the brain, 25 (29%) – developmental abnormalities of the brain, the remaining 23 (27%) cases – disorders within the framework of brain infections sustained during the development period. In 29 (33.7) children, the first seizures were found during the newborn period. Forty-nine (57%) children experienced seizures during the infant period. Seven (8%) children were diagnosed with West syndrome, 4 (57%) of them resolved with treatment, 3 (43%)-developed pharmaco-resistance. Eight (0.9%) children had febrile seizures during early childhood, 6 (75%) – exceeded them, 2 (25%)-developed epilepsy. Twenty – five (29%) children had focal epilepsy with convulsive manifestations and EEG discharges typical of early-onset infant epilepsy, and 19 (22%) - infantile epilepsy with centrotemporal peaks, 27 (61%) of them overcame these seizures. Fourteen (16%) children had generalized epilepsy with onset at the age of 8-15 months. Nineteen (22%) children the diagnosis evolved from one epileptic syndrome to another. The average age at the last follow – up is 13.3 years, and the minimum age is 8.9 years. In most children – 66 (76.7%) seizures resolved within a period of 2 years. Conclusions. CP is associated with various structural changes in the brain that are responsible for the occurrence and variability of epilepsy. Epileptic disorders in CP have various electroclinical characteristics and are limited to childhood age, having favorable evolution in most cases. Early recognition of epilepsy in children with CP has important implications for conducting management and determining prognosis.