Introduction: While alcohol addiction is a social problem in Romania, affiliation to Alcoholics Anonymous (AA) was found to have potential benefits in affiliated individuals. The purpose of this paper was to identify differences between highly affiliated and low/non-affiliated individuals who struggle with alcohol addiction and attend AA meetings in Romania. Methods: A mixed method research was conducted between May and June 2021 and included 24 participants (12 strongly AA affiliates and 12 low/non-affiliated individuals) from a sample of 155 participants. Questionnaires were used to collect data on spiritual, well-being, mental health and addiction related concepts. Correlations and T-tests were used to analyze the quantitative data. Semi-structured interviews were conducted in order to obtain a deeper insight. Interviews were audio-recorded, transcribed and analyzed using qualitative content analysis. Results: Findings from the questionnaire showed significant differences in length of sobriety, affective organizational commitment, overall number of completed AA Steps, positive religious coping, anxiety, craving, commitment to sobriety, confidence on staying sober, abstinence self-efficacy, and desire for abstinence. Two main themes emerged based on the interview data: characteristics of highly affiliated individuals, and characteristics of low and non-affiliated individuals. Discussion and Conclusion: The findings demonstrate that AA affiliation is associated with specific benefits in individuals who deal with alcohol addiction and that highly affiliated individuals are more likely to maintain sobriety, obtain spiritual benefits, improve their mental health and become committed to their recovery. Those working in the area of substance abuse should pay more attention to the benefits of successful affiliation to AA since they seem to play an important role in maintaining sobriety.