Introduction. Celiac disease (CD) is an autoimmune disease, with onset in childhood and develops in those with a genetic predisposition, sensitized by foods rich in gluten. Material and methods. Within the framework of the CD SKILLS DTP 571 Project funded by the European Union, we performed anti-tTG IgA rapid test screeing testing of 439 children aged between 9 months and 18 years who had suggestive digestive signs for CD. 41 of these children showed recurrent abdominal pain, being from the risk group - 30 with type I diabetes; 3 - autoimmune thyroiditis; 1 - with Down syndrome; 3 - with juvenile rheumatoid arthritis; 4 - with autism). At the same time, 100 adults aged between 19-65 who showed clinical signs of damage to the digestive system were tested. Results. Positive IgA anti-TG were detected in 1.03% (6 children) of cases, including: 4 (0.91%) children with clinical signs of abdominal pain and unstable stools and in 2 (4.87 %) children with type 1 diabetes. The complex examination confirmed celiac disease in all positive anti-tTG IgA cases with rapid tests. Adult patients screened for IgA anti-tTG were negative. Conclusion. Anti-tTG IgA screening with the use of rapid IgA anti-tTG tests proved to be positive in 1.03% of cases and is recommended at the initial stage of specifying the diagnosis of celiac disease in children. The definitive diagnosis of celiac disease requires examination and confirmation of the diagnosis according to the criteria approved by ESPGHAN 2020.