Introduction. Respiratory infections are among the leaders in morbidity worldwide, being frequently caused by the influenza virus. In this sense, the development of drugs against flu is an important task for the pharmaceutical field. Material and methods. The prescriptions of the doctors from the Vasile Procopișin UPhC for the period of 2022 served as materials. Results. The study of the specialized literature using the Medline and PubMed databases shows that, currently, there are effective anti-influenza preparations on the world pharmaceutical market, but doctors frequently opt for magistral formulations, which allow the individualization of doses and combinations of compatible medicinal substances, in formulations without industrial analog. In the Republic of Moldova, during the year 2022, magistral compounded powders were frequently prescribed for adults, with the composition: rutin 0.02, ascorbic acid 0.3, acetylsalicylic acid 0.5, diphenhydramine 0.03 and calcium gluconate 0.3, recommended to be administered for 10 days. The stability studies of these powders carried out in the drug technology department demonstrated their physico-chemical stability for up to 30 days. Conclusions. The use of compoundeded anti-influenza formulations have proven to be very effective, stable and well tolerated by patients and also prevent the further development of the disease and the appearance of possible complications.