Non-alcoholic fatty liver disease and advanced liver fibrosis in patients with type 2 diabetes
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STUPELIMAN, Galina, HAREA, Dumitru. Non-alcoholic fatty liver disease and advanced liver fibrosis in patients with type 2 diabetes. In: Perspectives of the Balkan medicine in the post COVID-19 era: The 37th Balkan Medical Week. The 8th congress on urology, dialysis and kidney transplant from the Republic of Moldova “New Horizons in Urology”, Ed. 37, 7-9 iunie 2023, Chişinău. București: Balkan Medical Union, 2023, Ediția 37, p. 113. ISSN Print: ISSN 1584-9244 ISSN-L 1584-9244 Online: ISSN 2558-815X.
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Perspectives of the Balkan medicine in the post COVID-19 era
Ediția 37, 2023
Congresul "Perspectives of the Balkan medicine in the post COVID-19 era"
37, Chişinău, Moldova, 7-9 iunie 2023

Non-alcoholic fatty liver disease and advanced liver fibrosis in patients with type 2 diabetes


Pag. 113-113

Stupeliman Galina, Harea Dumitru
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 20 decembrie 2023


Rezumat

Introduction. Non-alcoholic fatty liver disease (NAFLD) is recognized worldwide as the most prevalent chronic liver disease with a high frequency among patients with type 2 diabetes (T2DM). This study aimed assessing the frequency of nonalcoholic fatty liver disease and advanced liver fibrosis in patients with type 2 diabetes. Material and methods. The cross-sectional study included 300 patients with T2DM (174 women and 126 men, with an average age of 58,94 ± 8,55 years), hospitalized between January and December 2022, in IMSP SCR "Timofei Moșneaga", Chisinau, Republic of Moldova. For evaluation were used the FLI calculator and the NAFLD Fibrosis Score. Results. Among the 300 patients included in the study, NAFLD is present in 75,67%. Analysis of the frequency of NAFLD according to gender showed no statistically significant differences between women and men. Analysis of the distribution of NAFLD according to BMI indicated that 76,2% of patients are obese. Using the NAFLD Fibrosis Score in patients with T2DM and NAFLD, it was found that advanced liver fibrosis (AdLF) was present in 18,50% patients (F3-F4), in 17,18% AdLF was excluded (F0- F2), and 64,32% patients presented an indeterminate score for AdLF. Conclusion. NAFLD is present in most patients with type 2 diabetes and especially in those with obesity. Most patients with NAFLD have an indeterminate advanced liver fibrosis score.