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SM ISO690:2012 ROTARU, Lilia, CEBUC, Madalina, LUPUŞOR, Adrian, GROSU, Oxana, ODOBESCU, Stela, GAVRILIUC, Olga, MOLDOVANU, Ion. Sleep disorders in Parkinson’s disease patients. A case-control study. In: Abstract book of European Academy of Neurology Congress: MDS, Ed. 2023, 27-31 august 2023, Copenhagen. Copenhagen: International Parkinson and Movement Disorder Society, 2023, p. 506. |
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Abstract book of European Academy of Neurology Congress 2023 | |||||||
Congresul "Abstract book of European Academy of Neurology Congress " 2023, Copenhagen, Danemarca, 27-31 august 2023 | |||||||
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Pag. 506-506 | |||||||
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Objective: To determine the quality of sleep, the type of sleep disorders and their correlations with motorimpairment in Parkinson’s disease (PD) patients. Background: Sleep disorders frequently coexist with PD, having bidirectional infl uences and affecting thepatients’ quality of life. Method: 37 PD patients (the study group) and 40 non-PD patients (the control group) were included in thestudy; 33 men (59.9%) and 44 women (57.1%), of similar ages (37±8.5 vs. 40±14.8, years, p>0.05). Sleepquality indices were determined by Pittsburg Sleep Quality Index questionnaire (PSQI), PD motorimpairment – by UPDRS scale, PD phenotype – by tremor and akinesia scores (Tremor Score (TRScore) andAkinetic Rigid Score (ARScore)), quality of life – by the PDQ questionnaire. Results: Compared to the control group, PD patients had a higher PSQI score (6.76±4.21 vs. 4.50±1.80,p=0.003) of which the worse subjective quality of sleep (PSQI score 1.08±0.76 vs. 0.55± 0.22, p=0.001) andthe lower sleep effi ciency (PSQI score 0.86±0.06 vs. 0.45 vs. 0.13, p=0.039) being the main contributors. PDpatients more frequently reported sleep disorders (45.7% vs. 67.5%, p=0.047), nocturnal awakenings (65.5%vs. 35.9%, p=0.027) and sleep-disordered breathing (65.7% vs. 42.5 %, p=0.037). The general quality of sleep,expressed by the PSQI score, signifi cantly correlated with the UPDRS motor score (r=0.369, p=0.029),in particular with the Akinetic Rigid Score (ARScor: r=0.434, p=0.009) and the quality of life inverselycorrelated with sleep duration (r=-0.312, p=0.010). Conclusion: General sleep quality and sleep effi ciency are reduced in PD patients, mainly due to sleepdisturbances, night awakenings and sleep-disordered breathing. Reduced overall sleep quality stronglycorrelates with the degree of motor impairment and akinesia, and reduces quality of life in PD patients. To cite this abstract in AMA style: L. Rotaru, M. Cebuc, A. Lupușor, O. Grosu, S. Odobescu, O. Gavriliuc, I. Moldovanu. Sleep disorders inParkinson’s disease patients. A case-control study. [abstract]. Mov Disord. 2023; 38 (suppl 1).https://www.mdsabstracts.org/abstract/sleep-disorders-in-parkinsons-disease-patients-a-case-control-study/. Accessed December 4, 2023. MDS Abstracts - https://www.mdsabstracts.org/abstract/sleep-disorders-in-parkinsons-disease-patients-a-case-control-study/ III 39 TOTAL 1 4 TOTAL 3 |
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