Articolul precedent |
Articolul urmator |
175 0 |
Căutarea după subiecte similare conform CZU |
611.13:616-092.9 (1) |
Anatomy. Human and comparative anatomy (240) |
Pathology. Clinical medicine (7212) |
SM ISO690:2012 ЛЕБЕДЕВА, Е.Ю.. Морфометрические показатели междольковых артерий крыс при экспериментальном циррозе печени. In: Actual issues of morphology, 30-31 octombrie 2020, Chişinău. Chişinău: Tipogr.-Sirius, 2020, pp. 147-151. ISBN 978-9975-57-281-1. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Actual issues of morphology 2020 | ||||||
Conferința "Actual issues of morphology." Chişinău, Moldova, 30-31 octombrie 2020 | ||||||
|
||||||
CZU: 611.13:616-092.9 | ||||||
Pag. 147-151 | ||||||
|
||||||
Descarcă PDF | ||||||
Rezumat | ||||||
The research of this work was to study the morphometric parameters of interlobular arteries in rats with experimental liver cirrhosis. Liver cirrhosis in Wistar rats was induced with thioacetamide at a dose of 200 mg / kg of animal weight twice a week for 17 weeks. The studied rats were randomized into 9 groups of 12 animals each. The diameter of the lumen and the thickness of the media of the interlobular arteries in μm were measured on histological preparations using ImageScope Color, cellSens Standard image analysis software and an OLYMPUS BX51 microscope. The Kernogan index was calculated.The results were processed using Statistica 10.0 software from StatSoft, IBM SPSS Statistics 23.0, Microsoft Office Excel. Based on the data obtained, it was found that in liver cirrhosis, changes in the lumen and thickness of the media of interlobular arteries do not have a definite pattern. Perhaps this is due to the compensatory-adaptive reactions of the organ and / or to the fact that the interlobular arteries of the rat liver during fibrogenesis are quite stable. An increase in the Kernogan index of interlobular arteries indicates a deterioration in vascular capacity at certain stages of the experiment (stages of fibrosis / cirrhosis), which must be taken into account when conducting preclinical studies. |
||||||
Cuvinte-cheie liver cirrhosis, rats, morphometric parameters of interlobular art |
||||||
|
Dublin Core Export
<?xml version='1.0' encoding='utf-8'?> <oai_dc:dc xmlns:dc='http://purl.org/dc/elements/1.1/' xmlns:oai_dc='http://www.openarchives.org/OAI/2.0/oai_dc/' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xsi:schemaLocation='http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd'> <dc:creator>Lebedeva, E.I.</dc:creator> <dc:date>2020</dc:date> <dc:description xml:lang='en'><p>The research of this work was to study the morphometric parameters of interlobular arteries in rats with experimental liver cirrhosis. Liver cirrhosis in Wistar rats was induced with thioacetamide at a dose of 200 mg / kg of animal weight twice a week for 17 weeks. The studied rats were randomized into 9 groups of 12 animals each. The diameter of the lumen and the thickness of the media of the interlobular arteries in μm were measured on histological preparations using ImageScope Color, cellSens Standard image analysis software and an OLYMPUS BX51 microscope. The Kernogan index was calculated.The results were processed using Statistica 10.0 software from StatSoft, IBM SPSS Statistics 23.0, Microsoft Office Excel. Based on the data obtained, it was found that in liver cirrhosis, changes in the lumen and thickness of the media of interlobular arteries do not have a definite pattern. Perhaps this is due to the compensatory-adaptive reactions of the organ and / or to the fact that the interlobular arteries of the rat liver during fibrogenesis are quite stable. An increase in the Kernogan index of interlobular arteries indicates a deterioration in vascular capacity at certain stages of the experiment (stages of fibrosis / cirrhosis), which must be taken into account when conducting preclinical studies.</p></dc:description> <dc:source>Actual issues of morphology () 147-151</dc:source> <dc:subject>liver cirrhosis</dc:subject> <dc:subject>rats</dc:subject> <dc:subject>morphometric parameters of interlobular art</dc:subject> <dc:title>Морфометрические показатели междольковых артерий крыс при экспериментальном циррозе печени</dc:title> <dc:type>info:eu-repo/semantics/article</dc:type> </oai_dc:dc>