Limited Nosocomial Transmission of Drug-Resistant Tuberculosis, Moldova

Noroc Ecaterina; Chesov Dumitru; Merker Matthias; Groschel Matthias I.P.; Barilar Ivan; Dreyer Viola; Ciobanu Nelly; Reimann  Maja; Krudu V.; Lange Christoph G.

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2023-09-13 17:35

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NOROC, Ecaterina, CHESOV, Dumitru, MERKER, Matthias, GROSCHEL, Matthias I.P., BARILAR, Ivan, DREYER, Viola, CIOBANU, Nelly, REIMANN , Maja, KRUDU, V., LANGE, Christoph G.. Limited Nosocomial Transmission of Drug-Resistant Tuberculosis, Moldova. In: Emerging Infectious Diseases, 2023, vol. 5, pp. 1046-1050. ISSN 1080-6040. DOI: https://doi.org/10.3201/eid2905.230035

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Emerging Infectious Diseases

Volumul 5 / 2023 / ISSN 1080-6040 /ISSNe 1080-6059

Limited Nosocomial Transmission of Drug-Resistant Tuberculosis, Moldova

DOI:https://doi.org/10.3201/eid2905.230035

Pag. 1046-1050

Noroc Ecaterina¹, Chesov Dumitru²³, Merker Matthias³⁴, Groschel Matthias I.P.⁵, Barilar Ivan⁴³, Dreyer Viola³, Ciobanu Nelly¹, Reimann Maja³⁴⁶, Krudu V.¹, Lange Christoph G.³⁴⁶

¹ Institute of Phtysiopneumology „Chiril Draganiuc”,
² ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
³ Research Center Borstel,
⁴ German Centre for Infection Research (DZIF), Partner Site Hamburg-Luebeck-Borstel-Riems,
⁵ Charité - University Medicine Berlin,
⁶ University of Lübeck

Disponibil în IBN: 12 iunie 2023

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Rezumat

Applying whole-genome-sequencing, we aimed to detect transmission events of multidrug-resistant/rifampin-resistant strains of Mycobacterium tuberculosis complex at a tuberculosis hospital in Chisinau, Moldova. We recorded ward, room, and bed information for each patient and monitored in-hospital transfers over 1 year. Detailed molecular and patient surveillance revealed only 2 nosocomial transmission events.

Cuvinte-cheie
Antitubercular Agents, Cross Infection, drug resistance, multiple, Bacterial, Humans, Microbial Sensitivity Tests, Moldova, Mycobacterium tuberculosis, tuberculosis, Multidrug-Resistant