Due to their vast useful applications, coordination compounds based on transition metal and multicarboxylate ligands are thoroughly researched. They can self-assemble metal-organic units through hydrogen bonds and π-π interac-tions to produce extended supramolecular structures with a variety of topologies and architectures. The correct choice of the metal ion and ligand is essential to designing the desired structure. Polycarboxylic ligands make excellent candidates because, depending on the quantity of the deprotonated carboxylic groups, they can serve as both a proton donor and an acceptor in the hydrogen bond. 1,3-bis(3-aminopropyl)tetramethyldisiloxane is a significant silicone derivative that can be used because it incorporates siloxane sequences into a variety of siloxane-organic compounds with reactive group content. The metal complexation primarily benefits greatly from the last functional group. Tetramethyldisiloxane, which has a high degree of flexibility, may give these compounds greater conformational flexibility that is helpful in catalysis. In addition, due to their high hydrophobicity, these compounds may be more soluble in common organic solvents and experience fewer thermal transitions, which will make them easier to process. Future applications of the produced derivatives in the biomedical field will benefit from the siloxane's biocompatibility and physiological inertness. The obtained structures could be viewed as sensitive, changing reversibly in response to stimuli like temperature or solvent traces.