Introduction: Psychiatric symptoms during pregnancy can vary from mild disorders to severe depressive episodes with psychotic symptoms, agitation, delusions or exacerbation of severe mental illnesses. The therapeutic approach is often difficult because of the risk of malformations or other consequences for fetus. Material and methods: The paper is dedicated to use of herbal medicines during pregnancy in patients with schizophrenia. Have been assessed 23 of the most commonly used herbal medicines, focusing on the pharmacokinetics and possible long-term effects on neonatal development of the newborns. Results and discussion: Meta-analysis studies have discovered an increased number of complications during pregnancy and postpartum in women with schizophrenia, namely gestational diabetes, preeclampsia/eclampsia, placental abruption. Some of these could be caused by pharmacological intervention during pregnancy. On the other hand, there was a tendency to use natural medicines, which, from the point of view of patients or doctors, would not have side effects similar to pharmacotherapy. A meta-analysis study of 1,067,071 women who used a total of 47 herbs suggests that "The use of herbal medicines during pregnancy and the postpartum period is not recommended until there is good evidence of their safety." [Yolanda Muñoz Balbontín et al., 2019]. Natural plants approved for use by the American Mental Health Association [2022] during pregnancy include Peppermint Leaf, Lemon Balm, Chamomile (German), Nettles (Stinging Nettles),Alfalfa. Although, assessing the possible risks, the association states "probably safe remedies" for all the above plants, except for German chamomile, where the risks are assessed as "insufficient reliable information" Conclusions: Herbal remedies as adjunctive natural treatment are frequently used in combination with psychotropic medications for anxiety, depression, and severe mental illnesses such as schizophrenia and bipolar affective disorder. Dietary supplements and herbal remedies can influence the clinical picture, biochemical and even genomic changes associated with pregnancy.