In this paper we present interesting paleontological and palynological investigations of the Satsurblia cave, Western Georgia. The Satsurblia cave was discovered by K. Kalandadze in 1974. The site was excavated in 1975 by the expedition of the Center for Archaeological Studies of Georgian Academy of Science in 1975, which has been lead by A. Kalandadze. Next campaigns took place in 1976, 1985-1988, 1990-1993, lead by K. Kalandadze. Since 2008 in the Saturblia cave an international archaeological expedition was carried out (the head of the expedition: T. Meshveliani). There were collected very interesting archaeological materials. We have important paleontological and palynological information about this site. The taxonomic composition of Upper Paleolithic layers is similar and dominated by large ungulates, mainly boar (Sus scrofa) and red deer (Cervus elaphus), which make up more than half of the identifi ed elements in these assemblages. Other ungulates represented include large bovidae (Bos primigenius and/or Bison priscus), tur (Capra caucasica), and roe deer (Capreolus capreolus). Palynological investigations show us that the sediments are rich in both pollen and other organic remains of non-palynological character. Those include wood cells, spores of various fungi, microscopic remains of insects and other arthropods, and textile fi bers. More than 40 soil samples originating from various strata of the cave were analyzed. The analysis has shown that climatic factors played a major part in the occupational history of the cave. Humans inhabited the cave mostly during warm and dry climatic phases. During humid and cold periods there was some standing water within the cave, at least in Area A, as is evident from remains of algae found in the samples. This subject and other interesting information will be presented in our report with many important details and innovative data.