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Articolul urmator |
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SM ISO690:2012 EŞANU, Valeriu, PALII, Ina. Impact of the glycated hemoglobin on the left ventricular mass index in children with type 1 diabetes mellitus. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 366. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Pag. 366-366 | ||||||
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Background. The presence of high left ventricular mass index (LVMI) is reportedly an independent predictor of increased cardiovascular morbidity and mortality. However, data regarding the association between glycated hemoglobin (HbA1c) and LVMI in children with type 1 diabetes (T1D) are limited. Objective of the study. Evaluation of the effect of glycated hemoglobin on LVMI in children with T1D. Material and Methods. 30 children with T1D (mean age = 13.8 ± 1.8 years; gender M (17) / F (13); duration of T1D = 6.69 ± 2.34 years) were submitted to clinical evaluation, laboratory tests (HbA1c level), and echocardiography (LV function and structure). Statistical analysis – SPSS version 20. The research received a favorable opinion of the Research Ethics Committee of the "NicolaeTestemitanu" SUMPh. Results. The correlational study between the HbA1c and the LVMI revealed a statistically significant positive correlation coefficient (r = 0.5*, p = 0.038). also with other parameters of the structure and function of the LV: LV diastolic diameter (mm) (r = 0.7**, p < 0.001), LV systolic diameter (mm) (r = 0.7**, p < 0.001), interventricular septal thickness at end-diastole (mm) (r = 0.5*, p = 0.036), posterior wall thickness at end-diastole (mm) (r = 0.5*, p = 0.032), LV diastolic volume (ml) (r = 0.5*, p = 0.025), LV systolic volume (ml) (r = 0.6**, p = 0.01), LV ejection fraction (%) (r = 0.7**, p = 0.001), LV fractional shortening (%) (r = 0.6**, p = 0.002). Conclusion. The results of the study confirm that the increased value of the glycated hemoglobin was associated with a consensual and proportional increase of the value of left ventricular mass index - marker for pathological ventricular remodeling, but, and with other parameters of the left ventricle. |
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Cuvinte-cheie glycated hemoglobin, left ventricular mass index, hemoglobină glicată, indicele de masă ventriculară stângă |
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