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616.24-008.844:612.12-008.312.2 (1) |
Pathology of the respiratory system. Complaints of the respiratory organs (777) |
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![]() LUPUŞOR, Adrian, DIACONU, Nadejda. Correlation between obstructive sleep apnoea syndrome and cognitive impairment in atrial fibrillation patients. In: World Sleep Congress, 7 octombrie - 11 noiembrie 2017, Prague. Prague, Czech Republic: World Sleep Society, 2017, Ediția a 14-a, p. 598. |
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World Sleep Congress Ediția a 14-a, 2017 |
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Congresul "World Sleep Congress" Prague, Cehia, 7 octombrie - 11 noiembrie 2017 | |||||||
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CZU: 616.24-008.844:612.12-008.312.2 | |||||||
Pag. 598-598 | |||||||
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Introduction: Obstructive Sleep Apnea Syndrome (OSA) appears to be involved in the cognitive decline. Atrial fibrillation (AF) may produce multiple cerebral ischemic areas due to microembolic phenomena and transient hypoperfusion, eventually leading to a progressive cognitive impairment and even to acclaimed vascular dementia. In the same time, OSA is common among patients with atrial fibrillation. The aim of this study was to evaluate the prevalence of cognitive impairment in patients with AF and OSA. Methods: We studied 82 patients with a history of non valvular AF and 40 homogenous controls in sinus rhythm (SR). All subjects underwent anamnesis, physical examination, cardiorespiratory monitoring during sleep (CRMS). The cognitive function was assessed using the Mini-Mental State Examination (MMSE). Results: A total of 122 patients (64,4% were men), were included in the study. The mean age of participants were 66.5, and the mean baseline MMSE score was 27.7. Based on the CRMS 78 (64%) of patients had OSA with a mean of apnea-hypopnea index equal to 27.5±17.1 (mean ±SD), 62% of them being with AF. The comparison between patients with AF and OSA and patients with AF without OSA, showed a lower index of MMSE score (24±2.3 vs. 26,8 ± 1,5, p< 0,01). Conclusion: Association of OSA an FA rises the probability for cognitive decline. Frequently coexisting OSA components in AF patients from primary care setting should encourage more active search of OSA and cognitive impairment in patients with documented AF. |
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