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543.422.3:546.32 (1) |
Spectral analysis methods. Optical analysis methods (69) |
Metals in general (37) |
![]() MAZUR, Ecaterina, UNCU, Livia. Determinarea orotatului de potasiu în amestec mecanic cu spironolactonă, aspartat de potasiu și magneziu prin spectrofotometrie UV-VIS. In: Revista Farmaceutică a Moldovei , 2021, nr. 3(47-S), pp. 27-31. ISSN 1812-5077. |
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Revista Farmaceutică a Moldovei | ||||||
Numărul 3(47-S) / 2021 / ISSN 1812-5077 | ||||||
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CZU: 543.422.3:546.32 | ||||||
Pag. 27-31 | ||||||
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Rezumat | ||||||
The UV-Vis spectrophotometric method was successfully used in the analysis of potassium orotate (OP) in a mechanical mixture with spironolactone (SP), aspartate of potassium (AP) and aspartate of magnesium (AM). Spectrophotometric dosage technique for potassium orotate in mechanical mixture with different combinations of these substances was developed. The absorbance of the solutions of the individual substances and in the mixtures based on 0.1 M NaOH solution was determined. OP showed absorbance at 286 nm and SP showed two absorptions max at 248 and 292 nm. AP and AM do not have absorbance in the UV region due to the lack of chromophore groups. From the obtained results, the content of OP in the mechanical mixture (1:1) with SP was 101.3% (RSD 0.23%). |
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Cuvinte-cheie UV-vis spectrophotometry, fixed-dose combination drugs, potassium orotate, spectrofotometrie UV-VIS, medicament combinat, orotat de potasiu |
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