This report emphasizes the most relevant achievements obtained in the coordination chemistry in the Republic of Moldova. The main results of scientific investigations of the Moldovan research centres are presented, as well as the most important successes attained in various areas of inorganic, coordination, bioinorganic, and quantum chemistry. Historically, chemical science in Moldova started in the 1940s with investigations in the area of coordination compounds of transition metals, in particular, of dioximates of d-metals, the study of the structure and properties of this class of compounds using the newest, at that time, physical methods of research. Later, the range of scientific themes significantly expanded, comprising template processes, topochemical synthesis, obtaining of mono- and polynuclear coordination compounds, including those with macrocyclic and chelating ligands; the synthesis of biologically active complexes,development of the theory of electronic and vibronic structure of compounds with mixed valence, etc., optimization of quantum-chemical research techniques, as well as of methods of the molecular design of biologically active systems, with the focus on their action mechanism. In 2006 the Centre of “Physical Chemistry and Nanocomposites” was created at the Institute of Chemistry, hence the research with the view of obtaining nanoparticles has started. The aims of the Centre are to investigate the formation of nanoparticles and to elaborate the methods of their production required in nanoelecronics; to elaborate advanced technologies, to produce new substances necessary for the national economy for the development of alternative energy sources, of new medicinal preparations, applications in agriculture, solving the issues of environmental protection. During the past years, Moldovan scientists intensively investigated mono- and polynuclear coordination compounds of metals (transition and s-type) as photo-catalysts, MOFs for gas storage and as nanostructurated materials for water photolysis. Other current directions of investigations are: obtaining inhibitors of cancer cells proliferation; preparing materials with useful magnetic properties, good for various applications including agriculture (as plant growth stimulators). The report will reflect also the contribution of the famous Moldovan inorganic chemists - professors Constantin Turta and Mihail Revenco, into the developement of the coordination and supramolecular chemistry in the Republic of Moldova and the main scientific achievements of the both.