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Ultima descărcare din IBN: 2019-09-13 08:55 |
SM ISO690:2012 ROTARU, Victoria. Rolul citokinelor proinflamatoare în patogenia şocului hemoragic
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2008, nr. 1(9), pp. 120-127. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 1(9) / 2008 / ISSN 1857-1719 | ||||||
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Pag. 120-127 | ||||||
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The role of proinflammatory cytokines in the pathogenesis of hemorrhagic shock
The blood serum concentration of the proinflammatory cytokines IL-1α, IL-6, TNFα
was studied in experiments in the rabbits with untreated hemorrhagic shock; also a group at animals resuscitated with Ringer's solution and hyaluronic acid has been investigated. In hemorrhagic shock elevation of the cytokines level in the blood takes place, Resuscitation with Ringer's solutin is characterized by the increase in the blood concentration of IL-1α, IL- 6 in comparasion with untreated shock. Resuscitation with hyaluronic acid enables blood cytokines concentration to decrease in comparison with untreated shock and resuscitation with Ringer's solution. The role of proinflammatory cytokines in the pathogenesis of
hemorrhagic shock and post transfuzion syndrome is discussed. |
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